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Texas Longhorns running back Quintrevion Wisner (5) runs down the sideline during the first half against the Texas A&M Aggies at Darrell K Royal-Texas Memorial Stadium on Nov. 28, 2025. (Scott Wachter/Imagn Images)

Week 4 of the College Football schedule is delivering some excellent games and matchups and there are plenty of ways for you to bet on the action all day long from sportsbooks like FanDuel, Caesars Sportsbook, Fanatics Sportsbook, and bet365. 

The main event for today is the matchup between Texas and Tennessee. We have the top ranked Longhorns going on the road to face Tennessee. The Volunteers haven’t fared well against top ranked teams in their history, but if they can get their running game going, an upset might be in order. 

Iowa vs. Michigan features two teams right next to each other in the standings. Iowa is 17th, and Michigan is 18th. It seems like the Wolverines have been flirting with a loss all season, and Iowa is poised to try to deliver it. Big 10 matchups are always fun to watch, and this could come down to whichever team can make a big pass at a critical time. 

This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX News may be compensated. This content was created by a team that works independently from the FOX newsroom.

One other great matchup worth watching tonight is Ole Miss heading into Gainesville, Florida to face the Gators after a very emotional victory last week. How quickly can Ole Miss refocus and prepare for another big test - this time on the road? Will Florida be able to hang with one of the toughest teams in the nation? The answer to these questions comes at 3:30 ET. 

Texas vs Tennessee

Odds subject to change

Iowa vs Michigan

Odds subject to change

Ole Miss vs. Florida

Odds subject to change

Oregon vs USC

Odds subject to change

 

Noon Window (12:00 PM ET)

Early Afternoon Window (1:00 PM – 2:00 PM ET)

Mid-Afternoon Window (3:00 PM – 4:30 PM ET)

Late Afternoon / Evening Window (5:00 PM – 7:00 PM ET)

Prime Time Window (7:00 PM – 8:00 PM ET)

Late Night Window (9:00 PM ET and later)

This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX News may be compensated. This content was created by a team that works independently from the Fox newsroom.

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