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NANO Nuclear Energy Inc. (NASDAQ:NNE) is one of the best nuclear energy stocks to buy as SMRs go mainstream, with a median upside potential of 66.1%.

On May 6, 2026, NANO Nuclear Energy Inc. (NASDAQ:NNE) signed a non-binding MOU with Supermicro, the global AI server and data center infrastructure leader. The agreement aims to explore the integration of NANO’s KRONOS MMR microreactors with Supermicro’s AI server racks, cooling systems, and lifecycle services. Together, the companies target self-powered, grid-independent AI data center infrastructure. Given that the work progresses well, both will deploy systems together and sell combined solutions.

The agreement is still in its early stage, with no committed revenue or deadlines. Yet the move bolsters the company’s strategic positioning, placing it at the intersection of two major long-term growth trends: advanced nuclear power development and rapid expansion of AI data center infrastructure. On the day of the announcement, NANO Nuclear Energy Inc. (NASDAQ:NNE) shares surged about 28% to roughly $29, reflecting the sharp market reaction.

That development follows the company’s recent technical and regulatory wins.

On April 28, 2026, NANO Nuclear Energy Inc. (NASDAQ:NNE) said its KRONOS microreactor design fits well within new, more flexible NRC licensing rules (Part 53 and proposed Part 57), though its first University of Illinois deployment will still be approved under the older Part 50 framework.

Meanwhile, on April 9, 2026, NANO Nuclear Energy Inc. (NASDAQ:NNE) announced that it received a DOE GAIN Voucher to work with Oak Ridge National Laboratory using NRC-recognized nuclear simulation tools (SCALE/TSUNAMI) to improve reactor safety modeling and advance pre-licensing and design development for its KRONOS microreactor system.

NANO Nuclear Energy Inc. (NASDAQ:NNE) is an advanced technology-driven nuclear energy company. Its business lines include cutting-edge portable and other microreactor technologies, nuclear fuel fabrication, nuclear fuel transportation, nuclear applications for space, and nuclear industry consulting services.

While we acknowledge the potential of NNE as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock.

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